We seek to provide insights into how brain function is disrupted in stress-related psychiatric and physiological disorders. We use diverse basic and translational research methods to identify molecular, neural, and behavioral signatures of these disorders. Through this integrative approach, we aim to improve understanding of how the brain copes with stress, which will ultimately improve our ability to design therapeutic interventions for stress-related mental and metabolic disorders. Our lab is an interdisciplinary research environment based in the Weizmann Institute of Science (Israel) and the Max Planck Institute of Psychiatry (Germany), led by Prof. Alon Chen.
Check out our new publication in Science Advances for a comprehensive single-cell molecular profile of the HPA axis.
Our latest publication in Neuron reveals new insights into how ketamine acts against depression.